Research Article

Structure basis for RNA-guided DNA degradation by Cascade and Cas3

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Science  06 Jul 2018:
Vol. 361, Issue 6397, eaat0839
DOI: 10.1126/science.aat0839

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vol. 361 no. 6397

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History: 
  • Received for publication January 23, 2018
  • Accepted for publication May 22, 2018

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Author Information

  1. Yibei Xiao1,*,,
  2. Min Luo2,,
  3. Adam E. Dolan1,
  4. Maofu Liao2,,§,
  5. Ailong Ke1,,§
  1. 1Department of Molecular Biology and Genetics, Cornell University, 253 Biotechnology Building, Ithaca, NY 14853, USA.
  2. 2Department of Cell Biology, Harvard Medical School, 250 Longwood Avenue, SGM 509, Boston, MA 02115, USA.
  1. Corresponding author. Email: ailong.ke{at}cornell.edu (A.K.); maofu_liao{at}hms.harvard.edu (M.L.)
  1. These authors contributed equally to this work.

  2. § These authors contributed equally to this work.

  • * Present address: State Key Laboratory of Natural Medicines, Department of Pharmacology, China Pharmaceutical University, Nanjing 210009, P. R. China.

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