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Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

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Science  21 Apr 2017:
Vol. 356, Issue 6335, pp. 307-311
DOI: 10.1126/science.aab3896

Article Information

vol. 356 no. 6335 307-311

PubMed: 
Print ISSN: 
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History: 
  • Received for publication 13 June 2016.
  • Accepted for publication 1 March 2017.

Author Information

  1. Thomas J. Park1,*,,
  2. Jane Reznick2,,
  3. Bethany L. Peterson1,
  4. Gregory Blass1,
  5. Damir Omerbašić2,
  6. Nigel C. Bennett3,
  7. P. Henning J. L. Kuich4,
  8. Christin Zasada4,
  9. Brigitte M. Browe1,
  10. Wiebke Hamann5,
  11. Daniel T. Applegate1,
  12. Michael H. Radke5,6,
  13. Tetiana Kosten2,
  14. Heike Lutermann3,
  15. Victoria Gavaghan1,
  16. Ole Eigenbrod2,
  17. Valérie Bégay2,
  18. Vince G. Amoroso1,
  19. Vidya Govind1,
  20. Richard D. Minshall7,
  21. Ewan St. J. Smith8,
  22. John Larson9,
  23. Michael Gotthardt5,6,
  24. Stefan Kempa4,
  25. Gary R. Lewin2,10,*
  1. 1Laboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.
  2. 2Molecular Physiology of Somatic Sensation, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
  3. 3Department of Zoology and Entomology, University of Pretoria, Pretoria, Republic of South Africa.
  4. 4Integrative Proteomics and Metabolomics, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
  5. 5Neuromuscular and Cardiovascular Cell Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
  6. 6German Centre for Cardiovascular Research (DZHK), Berlin, Germany.
  7. 7Departments of Anesthesiology and Pharmacology, University of Illinois at Chicago, Chicago, IL 60612, USA.
  8. 8Department of Pharmacology, University of Cambridge, Cambridge CB2 1PD, UK.
  9. 9Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
  10. 10Excellence Cluster Neurocure, Charité Universitätsmedizin Berlin, Berlin, Germany.
  1. *Corresponding author. Email: glewin{at}mdc-berlin.de (G.R.L.); tpark{at}uic.edu (T.J.P.)
  1. These authors contributed equally to this work.

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